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Assessing Vegf Mrna and Mir-494 Expression in Peripheral Blood Collected From Patients Suffering From Oral Squamous Cell Carcinoma
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نویسنده
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Masoum Khani Maryam ,Mohamadnia Abdolreza ,Hosseini Farzaneh ,Bayat Parisa ,Bahrami Naghmeh
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منبع
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Journal Of Craniomaxillofacial Research - 2019 - دوره : 6 - شماره : 1 - صفحه:34 -38
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چکیده
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Introduction: oral squamous cell carcinoma accounts for 2% of all cancers and also is one of the top 10 causes of death in humans. the goal of this article is to assess changes of vegf mrna and mir-494 expression. materials and methods: we chose 30 patients with oscc and 30 healthy people (as a controlled group) and assess the rate of vegf mrna and mir-494 expression in peripheral blood with real-time pcr technique.findings: vegf mrna marker was positive in 24 out of 30 patients. also, mir-494 was positive in 20 out of 30 patients. results: overall based on this article’s findings, results could count as a diagnostic screening test for oscc detection in early steps of cancer.
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کلیدواژه
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Oral Squamous Cell Carcinoma ,Early Diagnosis ,Vegf Mrna ,Mir-494
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آدرس
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Islamic Azad University, North Tehran Branch, Faculty Of Biological Sciences, Department Of Cell And Molecular Biology, Iran, Shahid Beheshti University Of Medical Sciences, Chronic Respiratory Diseases Research Center, School Of Advanced Technologies In Medicine, National Research Institute Of Tuberculosis And Lung Diseases (Nritld), Department Of Biotechnology, Iran, Islamic Azad University, North Tehran Branch, Department Of Microbiology, Iran, Tehran University Of Medical Sciences, Craniomaxillofacial Research Center, Iran, Tehran University Of Medical Sciences, School Of Advanced Technologies In Medicine, Craniomaxillofacial Research Center, Department Of Tissue Engineering And Applied Cell Sciences, Iran
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پست الکترونیکی
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n-bahrami@sina.tums.ac.ir
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Authors
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