the effect of eight weeks aerobic training and omega3 ingestion on the levels of ctrp-9 and adiponectin in overweight and obese women

Background: adiponectin and ctrp-9 are adipose tissue secreted adipokines mediating various tissue functions. objectives: the present study aimed to investigate the effect of eight weeks of aerobic training and omega-3 ingestion on the levels of ctrp-9 and adiponectin in overweight and obese women. methods: a total of 40 women within the age range of 20-35 years (mean age: 27.29±3.27 years) and mean body mass index of 29.6±1.93 kg.m2 participated voluntarily in the present study. the participants were then randomly assigned into four groups (10 cases per group) of placebo, omega-3, training, and training+omega-3. the aerobic training program lasted eight weeks (three sessions per week); moreover, the omega-3 and training+omega-3 groups consumed 2,000 mg of omega-3 supplements daily. blood samples were collected pre- and post-intervention (48 h after the last training session or omega-3 consumption). following that, adiponectin, ctrp-9, and insulin levels were measured by elisa. data analysis was performed using the analysis of covariance and bonferroni post-hoc test. results: a significant decrease in the ctrp-9 levels and insulin resistance, as well as a significant increase in the adiponectin levels in the training and training+omega-3 groups were observed, compared to the placebo and omega-3 groups (p<0.05). conclusion: based on our findings, it seems that the positive effects of aerobic training alone or combined with omega-3 supplementation are partially exerted by increased and decreased adiponectin and ctrp-9 levels, respectively. furthermore, omega-3 supplementation can increase the effectiveness of aerobic training by modulating ctrp-9 and adiponectin levels.