Effect of a resistance-power training and vitamin D supplementation on serum IGF-1 concentration and physical function in elderly women

Background: this research examined the effect of a period of resistance-power training and vitamin d supplementation on serum insulin-like growth factor 1 (igf-1) concentration and physical function in elderly women.objectives: this study aimed to evaluate the effect of 12 weeks of resistance-power training and vitamin d supplementation on serum igf1, vitamin d concentrations, and physical function of elderly women.methods: in total, 44 elderly volunteered women were randomly assigned to four groups of training+placebo (tp), training+vitamin d (ts), vitamin d (vit d), and placebo (p). the training groups performed a weight training program for 12 weeks (three sessions per week). people in the vit d group took one 50,000 iu vitamin d jelly tablet every two weeks, and the p group took one placebo capsule (rice flour). blood samples were taken from all subjects before and after training; moreover, serum vitamin d, igf-1, and physical function indices were measured in this study. data were analyzed in spss (version 25) and r3.5.2 software through the analysis of variance of weighted repeated measures. results: serum vitamin d was significantly increased in the ts and vit d groups in comparison with the control group, while it is meaningfully decreased in the tp group (p≤0.05). training and supplementation interventions had no significant effects on serum igf-1 (p≥0.05). there was a significant increase in the physical function indices of the ts and tp groups, compared to those in the control group (p≤0.05); meanwhile, there was no significant difference between the two groups.conclusion: resistance-power training in the elderly improved the physical function indices; however adding vitamin d supplementation to the training had no significant effect on physical function.