Study of hs-CRP Level in Prisoners in Mashhad and Their Relation to Demographic Factors

Background: prisoners are a certain part of the population. prisoners are kept in a closed environment for a long period of time and are prone to various diseases. inflammatory biomarkers, including hs-crp, are new risk factors for cardiovascular disease. objectives: the aim of this study was to compare hs-crp levels in male and female prisoners and investigate the relationship between hs-crp levels with related factors. methods: in this cross-sectional study, 316 prisoners in mashhad prison were investigated. a blood sample (7ml) was taken from each subject. enzyme-linked immunosorbent assay (elisa) technique was used to measure serum levels of highsensitivity c-reactive protein (hs-crp). descriptive statistics, chi-squared test, t-test, pearson and spearman’s correlation coefficients were used. p<0.05 was considered to be the level of significance. results: 316 prisoners were investigated of whom 211 (66.8%) were male and 105 (33.2%) were female. mean hs-crp level was 5.72±7.93 μg/ml in men and 7.48±8.39 in women. the difference between the two genders were statistically significant (p<0.001). the mean hs-crp level was significantly higher in prisoners who did injection drug use compared to those who inhaled or consumed drugs (p<0.001). a significant correlation was observed between age, systolic blood pressure, frequency of imprisonment, height and bmi and hs-crp levels. conclusion: since hs-crp is an important biomarker for non-communicable diseases, considering these factors and other risk factors for chronic diseases in the high-risk and vulnerable groups of prisoners, prevention and control measures can be planned by this group of people.