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Sex hormone-binding globulin in children and adolescents
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نویسنده
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aydın b. ,winters s.j.
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منبع
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journal of clinical research in pediatric endocrinology - 2016 - دوره : 8 - شماره : 1 - صفحه:1 -12
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چکیده
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Sex hormone-binding globulin (shbg) is a circulating glycoprotein that transports testosterone and other steroids in the blood. interest in shbg has escalated in recent years because of its inverse association with obesity and insulin resistance,and because many studies have linked lower circulating levels of shbg to metabolic syndrome,type 2 diabetes,nonalcoholic fatty liver disease,polycystic ovary syndrome,and early puberty. the purpose of this review is to summarize molecular,clinical,endocrine,and epidemiological findings to illustrate how measurement of plasma shbg may be useful in clinical medicine in children. © 2016,journal of clinical research in pediatric endocrinology,published by galenos publishing.
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کلیدواژه
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Metabolic syndrome; Non-alcoholic fatty liver disease; Obesity; Polycystic ovary syndrome; Sex hormone-binding globulin; Type 2 diabetes
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آدرس
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university of louisville,division of endocrinology,metabolism and diabetes,kentucky, United States, university of louisville,division of endocrinology,metabolism and diabetes,kentucky, United States
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Authors
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