Association of Ca×PO4 product with levels of serum C-reactive protein in regular hemodialysis patients

Introduction: numerous studies have attempted to identify risk factors for mortality and morbidity in maintenance hemodialysis patients. in this study we sought to examine the association of the levels of serum c-reactive protein (crp) with value of ca×po4 product, in stable hemodialysis patients.patients and methods: based on the severity of secondary hyperparathyroidism, patients being treated with oral active vitamin d3, calcium carbonate/renagel tablets at various doses. fasting serum 25-hydroxy vitamin d and intact serum parathormone and also serum blood urea nitrogen, crp, calcium, phosphorus, alkaline phosphatase was measured.results: a total of 41 patients, enrolled to the study. the mean patients’ age were 46(17.6) years. the value of serum crp of patients was 8.6 (6.6) mg/l (median 6 mg/l). the value of ca×po4 product was 50.5(15.5) mg^2/dl^2 (median: 50 mg^2/dl^2). in this study, a significant inverse association between ca×po4 product and the age of the patients was seen. a significant positive correlation of logarithm of serum crp with ca×po4 product was found.conclusion: the result of this study, revealed the need to further attention to hyperphosphatemia in hemodialysis patients.