Effects of mobile phone prolonged radiation on kidney cells; an in-vitro study

Introduction: mobile phones have been shown to have hazardous effects on the human renal system, reproduction and development, central nervous system and immune function. objectives: this study aimed to investigate whether the mobile phone prolonged radiofrequency (rf) radiation could affect healthy kidney cells in an in-vitro study. materials and methods: human kidney healthy cells in three groups were placed into three batches. the first and second groups (exposed groups) were exposed to a mobile phone simulator for 1 and 2 h/d, respectively. the irradiation was performed for 8 consecutive days. for the third group (control group), no radiation was applied to the samples and they completed the assay cycle under identical conditions. cells’ survival was evaluated using mtt [3-(4,5-dimethylthiazol–2-yl)-2,5-diphenyltetrazolium bromide] assay. statistical significance of the differences between control and exposed groups were assessed using the repeated measure anova method (p < 0.05). results: results showed that radiation exposure from mobile phones simulator decreased the kidney cell survival in the exposed groups (up to 40%). anova test revealed that a significant decrease in cell survival in the exposed group compared to the control group (p = 0.014). no significant differences between the irradiated groups were found (p > 0.05). conclusion: mobile phone exposure affects kidney cells survival during an in vitro condition. to study the effects of mobile phone radiation on kidney, further in vivo studies on mammalians are needed.