High-salt intake during pregnancy may influence the outcome of renal ischemia/reperfusion in in adultoffspring

Introduction: the salt diet during the pregnancy may disturb the adult offspring’s organs functions. objectives: this study was designed to determine the role of high salt intake during pregnancy on the outcome of renal ischemia reperfusion (ir) in adult offspring. materials and methods: renal ir was induced in 55 adult male and female offspring from mothers who intake high salt or normal drinking water during pregnancy, and the kidney function was evaluated. results: salt intake during pregnancy increased the serum levels of creatinine (cr) and blood urea nitrogen (bun) and decreased creatinine clearances (clcr) level in offspring after renal ir gender dependently. conclusion: the structural change in kidney of offspring from mothers who were subjected to salt intake during pregnancy may influence the outcomes of offspring’s kidney functions after renal ir.