Parameters of Coagulation in COVID-19 Patients: A Correlation with Clinical Severity

Introduction: covid-19 infection can be complicated by coagulation derangement and a high risk of thromboembolic episodes. our study aimed to investigate coagulation parameters in covid-19 patients and their correlation with clinical severity. methods: we analyzed coagulation parameters pt, aptt, d-dimer, and fibrinogen in 98 rt-pcr-confirmed covid-19 patients admitted to the government institute of medical sciences, gautam buddha nagar, uttar pradesh, india. results: this study involved 69 males (70.50%), and 29 (29.5%) were females. the mortality rate was 6.12% (n= 06). forty-six patients (46.94%) had comorbidities. thirty-four patients had elevated pt, and 7 had high aptt, whereas d-dimer and fibrinogen levels were raised in 68 and 61 patients, respectively. among all four parameters, d-dimer levels were significantly associated with disease severity. conclusion: derangement of ddimer levels is significantly associated with disease severity in covid-19 infection.