Sequential HCoV-HKU1 and SARS-CoV-2 Infections, a Case Report

In the sars-cov-2 pandemic, the seasonal viral respiratory infections had a minimum prevalence due to public health precautions to reduce the risk of getting coronavirus disease 19 (covid-19). there have been reports of covid-19 coinfection with influenza, respiratory syncytial virus (rsv), and seasonal coronaviruses during the pandemic. here, we report a case in which the patient had sequential respiratory infections of human coronavirus hku1 (hcov-hku1) and sars-cov-2 in a fully vaccinated, healthy person. it should be noted that other seasonal coronaviruses that could cause symptomatic rtis might be misdiagnosed clinically with covid-19. hence, we highly recommend monitoring and follow-up of symptomatic patients with negative sars-cov-2 rt-pcr results.