Anti-inflammatory and anti-microbial activities of aqueous leaves extract of Butea frondosa

Introduction: butea frondosa has been suggested to be very useful in treating inflammatory diseases but no scientific investigation has been done in such direction. in this study the anti-inflammatory and anti-microbial activities of leaves aqueous extract of b. frondosa were determined in infected and non-infected human whole blood against specific vaccine antigen, hbsag.methods: in order to explore the anti-inflammatory and anti-microbial activities of b. frondosa (0.5–0 mg/ml; 50 μl), infected (virally) and non infected (control) human whole blood samples were stimulated with hepatitis b vaccine containing surface antigen (hbsag, 20 μg/ml;10 μl) in order to determined its blood counts and proliferation assay.results: aqueous leaves extract of b. frondosa (10 mg/ml; 50 μl) containing hbsag inhibited the percentage count of monocytes as well as granulocytes population in both cases. in addition, this aqueous extract also reduced its proliferation rate at higher doses.conclusion: aqueous leaves extract of b. frondosa possesses both anti-inflammatory and antimicrobial activities and might be used for these purposes.