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chemical constituents and evidence-based pharmacological properties of physalis peruviana l.: an overview
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نویسنده
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kasali félicien mushagalusa ,kasali félicien mushagalusa ,tuyiringire naasson ,peter emanuel l. ,ahovegbe lucrèce y. ,ali muhammad shaiq ,tusiimire jonans ,ogwang patrick engeu ,kadima justin ntokamunda ,agaba amon ganafa
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منبع
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journal of herbmed pharmacology - 2022 - دوره : 11 - شماره : 1 - صفحه:35 -47
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چکیده
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Physalis peruviana l. is among plant species possessing evident nutritional, nutraceutical, and commercial interests. this review highlights the complexity of the chemical composition supporting the multiple pharmacotherapeutic indications and dietary values of this plant through evidence-based studies from google scholar, pubmed/medline, scifinder, science direct, scopus, the wiley online library, and web of science. the literature mentions at least 40 compounds isolated from different parts; others are still under investigation. high yields in carotenoids, amino acids, minerals, vitamin c, vitamin e, and essential fatty acids have healthy nutritional benefits. various phytoconstituents, particularly withanolides, exhibit anti-carcinogenic, anti-inflammatory and antidiabetic potentials, as well as cardiovascular and liver protective effects. prospective studies reveal that the leaves would also provide various beneficial bioactive chemicals worth being isolated. however, clinical evidence-based studies are seldom. therefore, adequate pharmaceutical formulations and more in- depth controlled clinical trials are needed to fill the gap.
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کلیدواژه
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physalis peruviana ,phytochemicals ,bioactivity ,pharmacological mechanisms ,therapeutic uses
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آدرس
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mbarara university of science and technology, pharm-biotechnology and traditional medicine center of excellence, uganda. official university of bukavu, faculty of pharmaceutical sciences and public health, department of pharmacy, congo, mbarara university of science and technology, pharm-biotechnology and traditional medicine center of excellence, uganda. official university of bukavu, faculty of pharmaceutical sciences and public health, department of pharmacy, congo, mbarara university of science and technology, pharm-biotechnology and traditional medicine center of excellence, uganda. university of rwanda, school of nursing and midwifery, college of medicine and health sciences, rwanda, mbarara university of science and technology, pharm-biotechnology and traditional medicine center of excellence, uganda. national institute for medical research, department of innovation, technology transfer & commercialization, tanzania, mbarara university of science and technology, pharm-biotechnology and traditional medicine center of excellence, uganda. university of abomey-calavi, isba, fast, laboratory of immunology, infectious and allergic diseases, benin, university of karachi, h.e.j. research institute of chemistry, international centre for chemical & biological sciences, pakistan, mbarara university of science and technology, faculty of medicine, department of pharmacy, uganda, mbarara university of science and technology, pharm-biotechnology and traditional medicine center of excellence, faculty of medicine, department of pharmacy, uganda. mbarara university of science and technology, faculty of medicine, department of pharmacy, uganda, official university of bukavu, faculty of pharmaceutical sciences and public health, department of pharmacy, congo. university of rwanda, school of medicine and pharmacy, college of medicine and health sciences, department of pharmacology, rwanda, mbarara university of science and technology, faculty of medicine, department of pharmacology and therapeutics, uganda
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پست الکترونیکی
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aagaba@must.ac.ug
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Authors
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