hypoglycemic effects of lagenaria siceraria, cynodon dactylon and stevia rebaudiana extracts

Introduction: the aim of the current analysis was to judge the hypoglycemic action of the phyto-extracts of lagenaria siceraria, cynodon dactylon and stevia rebaudiana using suitable in vitro approaches. methods: the hypoglycemic activity of the phyto-material extracts was evaluated by employing various in-vitro methods namely glucose diffusion, amylolysis kinetics and glucose adsorption capacity. results: the extracts of l. siceraria, c. dactylon and s. rebaudiana exhibited glucose dialysis retardation indices (gdri) of 48.14%, 37.03% and 29.62%, respectively at 60 minutes which were reduced to 15.78%, 10.52% and 18.42%, respectively at 120 minutes. all the plant extracts used in the study adsorbed glucose and their adsorptions markedly enhanced with increase in sugar concentration. conclusion: from the outcome of the assay it can be concluded that the extracts of l. siceraria, c. dactylon and s. rebaudiana have hypoglycemic activity as observed in various in-vitro assays. however, the beneficial actions require to be verified by adopting various in vivo techniques along with clinical trials for their efficient use as potential remedial moiety