Heterotopic pregnancy, which is rare after ovulation induction with clomiphene citrate and timed intercourse

The condition of the coexistence of intrauterine and extrauterine pregnancies is called as heterotopic pregnancy. the incidence is 1/30000 with natural conception and increases up to 1/100 with assisted reproductive techniques (art). clomiphene citrate, a drug for ovulation induction, is used as a treatment approach for the patients with oligo-ovulation and subfertility with normal estrogen levels. this treatment may lead to the development of more than one follicle, ovarian hyperstimulation and multiple gestations. increased estrogen level after ovulation induction disrupts tubal transport and increases ectopic pregnancy risk. in our case, we aimed to emphasize the difficulties of diagnosing heterotopic pregnancy, which is rare after ovulation induction with clomiphene citrate and timed intercourse, current diagnosis and treatment methods, as well as the importance of clinical and ultrasonographic evaluation of pelvic and adnexial structures of all terminated or ongoing first trimester pregnancies.