The role of mean platelet volume as a predictor of postoperative shunt occlusion in children who underwent modified blalock-taussig shunt surgery

Purpose:backgrounds:the modified blalock-taussig shunt (mbts) is a palliative procedure which is often performed to maintain additional pulmonary blood flow. postoperative shunt patency is critical in order to provide adequate systemic oxygenation. mean platelet volume (mpv) correlates with platelet function and there is a possible correlation between an increase in mpv and the risk of thrombosis. aim:the aim of this study was to determine the role of mpv as a potential risk factor in postoperative early shunt occlusion in children underwent mbts surgery. materials and methods:this study was carried out with 1117 women. body mass index was calculated by the formula: body weight/height (kg/m²), body composition was assessed by bioelectrical impedance analysis; waist circumference was measured and waist/height ratio was calculated. for determining the physical activity status of individuals, individual physical activity records were investigated. in addition, the variables associated with obesity were assessed in relation to bmi. results:in the majority of cases the operation was performed via thoracotomy (89.7%). the shunt was constructed between the subclavian artery and pulmonary artery in 187 cases. in the remaining 8 patients the shunt was connected to the innominate artery. twenty-three patients (11.8%) experienced early shunt occlusion. preoperative mpv levels were 8.2 (6.2-14.0) in no occlusion group and 8.3 (6.9-10.7) in occlusion group. neither mpv nor other variables showed a statistically significant association with early shunt occlusion conclusion:despite some other studies demonstrating an association between high mpv levels and thrombosis, we could not find any statistically significant association between mpv and early shunt occlusion.