Evaluation of urinary culture and urinalysis results of pediatric patients prediagnosed with urinary tract infection

Purpose:the present study aimed to determine the bacteria causing urinary tract infection and their antibiotic resistance rates, and to assess the diagnostic compliance along with the culture results of several urine analysis tests in pediatric patients aged 0–16 years in the present region. materials and methods:a retrospective analysis was performed to examine the results of a total of 982 urine samples received for both urine culture and analysis. these samples were of pediatric patients aged 0–16 years prediagnosed with urinary tract infection between march 2015 and february 2016. along with the urine culture results of the patients, leukocyte (≥10/ml) and nitrite positivity reviewed in the full automated urine analyzer was also evaluated. results:the most common bacteria identified in 196 patients in whom growth was detected in urine cultures were escherichia coli (72%), klebsiella pneumoniae (8.6%), proteus mirabilis (7.6%), enterococcus spp. (7%), and other species (4.8%), as per the order of frequency. in e. coli and k. pneumoniae isolates, no resistance was observed to amikacin, phosphomycine, nitrofurantoin, and imipenem, which were also found to be the most effective antibiotics. diagnostic sensitivity, specificity, positive predictive value, negative predictive value, and accuracy rates of leukocyte and nitrite positivity were calculated from the urinalysis tests by taking the culture results as reference. these values were found to be 64.3%, 95%, 76.4%, 91%, 88.4% for leukocytes and 17.1%, 99%, 86%, 83.5%, 69.8% for nitrites, respectively. conclusion:we can say that the antibiotic resistance rates in pediatric patients in our region are found to be lower compared to other studies. according to comparisons we have made, urinary analysis results are not diagnostic alone due to the low correspondence of culture results. the urinalysis tests used for rapid diagnosis will be useful for assessing the culture more efficiently by performing and following antibiograms to prevent the development of resistance.