A review on biological properties and mixed ligand metal complexes of 2-aminobenzothiazole

The studies about the structures and biological properties of the mixed ligand metal complexes (mn+, m = mn, fe, co, ni, cu, zn, ag, au, ru, os, ir, pd, rh, u, eu, and tb) of the 2- aminobenzothiazole and some organic compounds (β-picoline, γ-picoline isopicoline, acetylaceton, o-hydroxyacetophenone, 1,2-ethylenediamine, piperazine, n,n'-bis (4-antipyrylmethyl) piperazine, n,n'-tetra(4-antipyrylmethyl)-1,2- diaminoethane, phtalamide, malonimide, benzylacetone, tetramethylenesulphoxide, catechol, p-chlorophenoxyacetic acid, 7-oxobicyclo[2.2.1]-heptan 2,3 dicarboxylic acid, 2,2’-bipyridine, 1,10-phenanthroline, propionic acid, phenoxyacetic acid, 2-amino 3- allylbenzothiazole, saccharine, triphenylphosphine, trichloroacetic acid, adipic acid, 1,4-benzenedicarboxylic acid, succinic acid, formic acid, picric acid, amino acid, p-formylphenoxyacetik acid and 2,6-pyridinedicarboxylic acid) have been observed in the literature. in these compounds, 2-aminobenzothiazole connected to the metal from n or s or amine group of thiazole ring or take part in the structure as the complementary form. some biological properties such as antimicrobial, anticancer, antifungal, anti-inflammatory, antitumor and inhibition of carbonic anhydrase of these complexes are well-known.