Role of microRNAs (miRNAs) in tumor angiogenesis

Angiogenesis is a controlled process that occurs in; developmental events of embryonic and post embryonic periods, wound and tissue healing and also events of female reproductive system. nevertheless angiogenesis can be observed as an uncontrolled and so a pathological process in cancers, some inflammatory diseases and eye diseases. mirnas are non protein coding small rna molecules. the researches shoved that mirnas play some important roles in the cell. also the expression changes of some mirnas is associated with angiogenesis and cancer development. for these reasons in recent years, the interest on mirnas has increased in the studies aiming to understand molecular basis of cancer and treatment of it.