Chorion villus sampling for karyotyping at 11-14 weeks of gestation: Evaluation of 42 cases

Objective: to evaluate indications, maternal and gestational age distribution, invasive methods, and karyotype results of chorion villus sampling (cvs) procedures material-method: cvs results performed for karyotyping in high-risk pregnancies at suleyman demirel university obstetrics and gynecology clinics between january 2008-february 2013 were retrospectively investigated. results: forty-two cases were included. maternal age was between 18-25 years in 19%, 26-33 years in 36%, and 34-41 years in 45%. mean gestational week at the procedure was 11.2 ± 1.2 (range, 11-15 weeks). a chromosomal abnormality was detected in 35.7% (n=15) of the cases. there were no fetal losses during or after 72 hours of the cvs procedures. discussion: cvs is a valuable and relatively safe method for the detection of chromosomal abnormalities at early gestation.