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the relationship between some laboratory findings and the prognostic significance of phosphorus and 25-(oh) vitamin d3 values in sars-cov-2 cases
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نویسنده
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aci recai ,keskin adem
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منبع
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avicenna journal of medical biochemistry - 2022 - دوره : 10 - شماره : 2 - صفحه:108 -113
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چکیده
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Background: there are many articles in the literature about the importance of 25-(oh) vitamin d3 in severe acute respiratory syndrome coronavirus 2 (sars-cov-2) cases. however, there is no consensus on 25-(oh) vitamin d3 to predict the prognosis of sars-cov-2 cases. additionally, phosphorus, which has an important role in the cytokine storm, contributes to poor prognosis in sars-cov-2 cases. objectives: this study aimed to examine phosphorus and 25-(oh) vitamin d3 levels to predict the prognosis of covid-19. methods: a total of 230 sars-cov-2 cases and 230 healthy people were included in this study. roc curve analysis was performed for combined evaluation of phosphorus and 25-(oh) vitamin d3 levels. results: in the roc curve analysis, the area under curve (auc) was 0.9282, the sensitivity was 92.70%, and the specificity was 92.80%. phosphorus and 25-(oh) vitamin d3 levels showed negative correlations with procalcitonin, ferritin, d-dimer, c-reactive protein, neutrophil-lymphocyte ratio, and monocytelymphocyte ratio. conclusion: low phosphorus and 25-(oh) vitamin d3 levels may be indicators for poor prognosis in sars-cov-2 cases. conversely, normal phosphorus and 25-(oh) vitamin d3 levels may be indicators for a good prognosis in sars-cov-2 cases.
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کلیدواژه
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phosphorus ,sars-cov-2 ,25-(oh) vitamin d3 ,disease severity ,predictive medicine
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آدرس
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samsun training and research hospital, department of biochemistry, turkey, aydin adnan menderes university, institute of health sciences, department of medicine biochemistry, turkey
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پست الکترونیکی
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ademkeskin78@gmail.com
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Authors
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