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   the relationship between some laboratory findings and the prognostic significance of phosphorus and 25-(oh) vitamin d3 values in sars-cov-2 cases  
   
نویسنده aci recai ,keskin adem
منبع avicenna journal of medical biochemistry - 2022 - دوره : 10 - شماره : 2 - صفحه:108 -113
چکیده    Background: there are many articles in the literature about the importance of 25-(oh) vitamin d3 in severe acute respiratory syndrome coronavirus 2 (sars-cov-2) cases. however, there is no consensus on 25-(oh) vitamin d3 to predict the prognosis of sars-cov-2 cases. additionally, phosphorus, which has an important role in the cytokine storm, contributes to poor prognosis in sars-cov-2 cases. objectives: this study aimed to examine phosphorus and 25-(oh) vitamin d3 levels to predict the prognosis of covid-19. methods: a total of 230 sars-cov-2 cases and 230 healthy people were included in this study. roc curve analysis was performed for combined evaluation of phosphorus and 25-(oh) vitamin d3 levels. results: in the roc curve analysis, the area under curve (auc) was 0.9282, the sensitivity was 92.70%, and the specificity was 92.80%. phosphorus and 25-(oh) vitamin d3 levels showed negative correlations with procalcitonin, ferritin, d-dimer, c-reactive protein, neutrophil-lymphocyte ratio, and monocytelymphocyte ratio. conclusion: low phosphorus and 25-(oh) vitamin d3 levels may be indicators for poor prognosis in sars-cov-2 cases. conversely, normal phosphorus and 25-(oh) vitamin d3 levels may be indicators for a good prognosis in sars-cov-2 cases.
کلیدواژه phosphorus ,sars-cov-2 ,25-(oh) vitamin d3 ,disease severity ,predictive medicine
آدرس samsun training and research hospital, department of biochemistry, turkey, aydin adnan menderes university, institute of health sciences, department of medicine biochemistry, turkey
پست الکترونیکی ademkeskin78@gmail.com
 
     
   
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