DRUG-INDUCED GINGIVAL ENLARGEMENT TWO CASE REPORT

Drug-induced gingival enlargement occurs as a side effect of some systemic drugs. nifedipine drug used for the management of patients with hypertension and cyclosporine drug used to reduce organ transplant rejection are some of them. the mechanism of drug-induced gingival enlargement is not entirely understood, but it is clear that due to the multifac- torial influences. important dental plaque growth in gums, predisposing factors, sex, age, duration of treatment. drug- induced gingival enlargement, the elimination of local factors, a good oral hygiene and can be controlled by periodontal therapy. we report a case of gingival hyperplasia due to nifedipine and cyclosporine a use to draw attention to rare adverse effect of this drug.