MUCOSITIS RELATED TO CHEMOTHERAPY

Chemotherapy induced mucositis is a self-limited complication of systemic chemotherapy. it is mainly due to the chemotherapy induced dna damage of rapidly dividing epithelial cells and release and upregulation of reactive oxygene radicals. in addition to interfering oral nutrition, mucositis can also leads to systemic bacteriemia fungemia and viremia due to the destruction of mucosal barrier against microbial agents. although, several prophylactic and therapeutic approaches are available, most of them are ineffective. risk assesment and effective preventive treatment is mandatory.