DENTAL DEVELOPMENT ABNORMALİTIES AFTER CANCER THERAPY IN CHILDHOOD (Four Case Reports)

In childhood cancer survivors’ cases, it is well known that treatments with chemotherapy and radiotherapy have side effects on permanent tooth development. hypodontia, microdontia, taurodontism, temporamandibular joint disorders, malocclusion, root stunting and enamel hypoplasia can be considered as disturbances in dental development in children. the aim of the study is to present the longterm effects of chemotherapy and radiotherapy on permenant dentition in four childhood cancer survivors cases. four childhood cancer survivors patients diagnosed under age three were examined in two health centers (dokuz eylül university hospital and dr.behcet uz children’s hospital) for oral and radiographic diagnosis. one of the four is neuroblastoma, another is, remaing two clear cell sarcoma have had therapy for acute lymphoid leukemia. microdontia, hypodontia and enamel hypoplasia have been observed in oral and radiographic examinations after completing at least 5 years following the chemotherapy and radiotherapy. the age of the patient having therapy, type and dosage of the therapy can influence the structure of the teeth. for this reason, it is important to inform the parents of children who will receive cancer therapy in young ages about the effects and consequences of therapy on dental development.