THE ROLE OF REACTIVE OXYGEN SPECIES IN PERIODONTAL TISSUE DESTRUCTION

In periodontal diseases tissue destruction occurs in two ways; directly and indirectly. the bacteria colonized in gingival crevicular and periodontal pocket and enzymes derived from bacteria are resposible for directly destruction. indirectly destruction is the tissue destruction caused as a response of host tissue against bacterial factors. bacteria and bacterial metabolic enzymes causes polymorphonuclear leukocytes’ migration as chemotatic agent and inflammatuar response occurs by the activation of immunologycal system. activated polymorphonuclear leukocytes relaeses various reactive oxygen species to protect tissue from microorganisms. the aim of this review is looking at the mechanisms of periodontal tissue destruction and to show the role of the reactive oxygen species in periodontal tissue destruction.