MYOEPITHELIOMA OF THE PALATE: 2 CASE REPORTS

Myoepithelioma is a rare salivary gland tumour. the tumour account for less than 1% of all salivary gland tumours and usually affect patients in the fourth and fifth decades of life, without gender predilection. most of these tumours are located in the parotid gland, while others occur in the submandibular gland or in the accessory glands of the oral cavity. reportedly, they grow slowly and pursue a benign clinical course. diagnosis is based mainly on the histopathological features, although immunohistochemical analysis is useful to confirm myoepithelial origin of the tumour cells, which are positive for cytokeratin, vimentin, glial fibrilary acid protein, s-100 protein and muscle-specific actin to varying degrees. treatment of these tumours consists of surgical excision with tumour-free margins. the prognosis of benign myoepithelioma would appear to be good, provided surgical excision is complete. in this paper, we reported a case of myoepithelioma of the palatal region in a 43-year-old male and 63 year-old female patients with regard to clinical features and the literature was reviewed.