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   pediatric tumor resection and recon-struction: outcomes of osteoarticular allograft fix-ation with stabilized dynamized nailing technique  
   
نویسنده sami sam aliliu ,kargar khalil ,shams roshanak ,zareie bushra ,beheshti fard shahabaldin ,hamidzadehkhiavi amin
منبع journal of research in orthopedic science - 2024 - دوره : 11 - شماره : 4 - صفحه:213 -220
چکیده    Background: reconstructing large bone defects after lower limb tumor resection remains a challenge in pediatric orthopedics. while osteoarticular allografts offer a biological solution, achieving stable fixation and union is crucial to minimize complications such as fractures and nonunions. objectives: we aimed to explore a novel, stabilized, dynamized nailing technique (sdnt) to enhance outcomes in pediatric patients undergoing tumor resection and reconstruction.methods: between 2014 and 2024, 40 pediatric patients (mean±sd age: 11.85±2.93 years) with malignant bone tumors (70.73% osteosarcoma, 24.39% ewing sarcoma, 2.44% chondrosarcoma) underwent wide resection (≥2 cm margins) and reconstruction with fresh frozen osteoarticular allografts (ffoa) soaked in gentamicin. fixation was achieved using sdnt, a modified intramedullary nailing (imn) approach designed to promote union through controlled dynamization. patients were followed for a mean±sd of 33.68±20.58 months, with outcomes including union time, complications, and survival assessed via clinical and radiographic evaluations.results: the mean±sd union time was 9.71±3.05 months. complications occurred in 48.88% of patients, with delayed union (24.39%), infection (14.64%), and drop foot (4.88%) being the most common. notably, no fractures occurred except for nail bending (2.44%). survival was 70.73%, with a 29.27% mortality rate and 17.07% disease relapse. metastasis affected 29.27% of patients, primarily in the lungs (26.83%).conclusion: sdnt with osteoarticular allografts offers a promising approach for pediatric lower limb tumor reconstruction, achieving a low fracture rate and effective bone union despite a high overall complication rate. these findings suggest sdnt may improve mechanical stability compared to traditional fixation methods, warranting further investigation.
کلیدواژه pediatric bone tumors ,osteoarticular allograft ,stabilized dynamized nailing ,intramedullary nailing (imn) ,lower limb reconstruction ,tumor resection ,osteosarcoma ,ewing sarcoma ,bone union ,fresh frozen allograft ,gentamicin-soaked allograft
آدرس iran university of medical sciences, bone and joint reconstruction research center, school of medicine, department of orthopedics, iran, iran university of medical sciences, bone and joint reconstruction research center, school of medicine, department of orthopedics, iran, iran university of medical sciences, bone and joint reconstruction research center, school of medicine, department of orthopedics, iran, iran university of medical sciences, bone and joint reconstruction research center, school of medicine, department of orthopedics, iran, iran university of medical sciences, bone and joint reconstruction research center, school of medicine, department of orthopedics, iran, iran university of medical sciences, bone and joint reconstruction research center, school of medicine, department of orthopedics, iran. baqiyatallah university of medical sciences, school of medicine, department of orthopedic surgery, iran
پست الکترونیکی drahkh2000@gmail.com
 
     
   
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