Comparing the Effects of Vitamins C and D in Preventing Complex Regional Pain Syndrome AfterDistal Radius Fracture Treatment

Background: the inflammatory response following trauma is the possible pathophysiology ofcomplex regional pain syndrome (crps) i, caused by the release of pro-inflammatory factorsand neuropeptides. vitamins c and d are two antioxidants that can effectively prevent theoccurrence of crps i.objectives: the primary aim of this study was to compare the effectiveness of vitamins c and din preventing the occurrence of crps following the fixation of distal radius fractures.methods: the study was performed from january 1, 2018 to the end of december 2019. patientswho had fractured distal radius were candidates for external fixation and pcp. the patients weredivided into three groups: 1) receiving 500 mg of vitamin c daily for 50 days, 2) receivingan oral dose of vitamin d of 5000 iu weekly for 50 days, and 3) receiving no complementarymedicine (control group).results: of the 150 fractures, 62 type c3, 56 type c2, and 32 type c1 were observed, constituting41.3%, 37.3%, and 21.3% of the total. during the two follow-up sessions, crps occurred in 28patients (18.7%). among the 28 patients mentioned, 14 patients (50%) belonged to group c, 8patients (28.6%) belonged to group b, and 6 patients (21.4%) belonged to group a.conclusion: the use of vitamins c and d reduced the incidence of crps in patients with distalradius fractures. also, the use of these vitamins was significantly effective in improving crpsand reducing pain and rom limitation.