the prevalence of gram-negative microorganisms isolated from ventilator-associated pneumonia patients in the intensive care units of southwest of iran

Background: increasing microbial resistance is a severe threat to global public health. one of the most common diseases in the intensive care unit is ventilator-associated pneumonia. methods: the method of this research was non-interactive and descriptive. this study was carried out from january to march 2018, at the golestan hospital of ahvaz. patients with ventilator-associated pneumonia (vap) were included in the study. the prevalence of resistant gram-negative microorganisms was studied through reported laboratory antibiogram results of cultures. results: from 373 hospitalized patients, 38 (10.2%) were diagnosed with vap. from the 57 respiratory cultures performed, overall 90 microorganisms were isolated, from which enterobacter with 36 cases (39.5%) and e.coli with 28 cases (30.7%) were most frequently compared to other organisms. from the 90 organisms responsible for the infection, 43 cases (47.2%) were multiple drug-resistant (mdr) microorganisms and 47 (51.6%) were extensively drug-resistant (xdr) microorganisms. enterobacter and e.coli were the most prevalent mdr microorganisms with 17 cases (39.5%) and 13 (30.2%), respectively. also, these two microorganisms were the most abundant xdr microorganisms with 19 cases (40.4%) and 15 (31.9%), respectively. conclusion: the results show the requirement of robust antibiotic monitoring and the optimization of antibiotic use in order to prevent the progression of antibiotic resistance in these units.