management of patients hospitalized for diabetic foot infection: a local evaluation

Background: diabetic foot ulcer (dfu) is the most increasing-trend complication of dm over previous decades. the present study was implemented to determine precisely how dfu was managed in the most referral hospital in isfahan. methods: this prospective observational cross-sectional study was conducted from 1 july 2016 to 15 december 2017 in the biggest referral hospital, al-zahra, in isfahan, iran. the information was collected by a trained pharmacy student filling the designed checklist included: baseline characteristics, methods used to investigate the infected lesion, management of the infected wound, assessment of risk factors related to patient’s outcome. results: the mean (±s.d) age of patients was 59.13±10.80 years. the majority of our patients had affected with type 2 dm (96.3 %). most of the patient (61%) had wound with grade 3 in the wagner classification. lesions mainly involved toes (46.3%). the most lesions (42%) had a mean size of the 5-10 cm2.the most frequently prescribed combination antibiotics were meropenem and targocid® (teicoplanin) (34.1%), tazocin® (piperacillin + tazobactam) and targocid® (24.3%). mean (±sd) duration of parenteral therapy (alone or in associated with oral treatment) was 14.95±7.62 days. ulcer size (cm2) (p=0.04), and wagner classification (p=0.012) had significant association with unhealed ulcer. conclusion: although, our diabetic center is university-affiliated, there are still several points, and pitfalls must be considered and revised in dfu patients. obtaining microbiological sampling, antibiotic management and baseline assessment of wound in patients are the most troublesome complications discovered by our investigation.