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monoclonal antibodies and its clinical aspects
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نویسنده
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shafras mohamadu maharuf mohamed ,ahamed mohamed rafeek rukshan ,pant geetika
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منبع
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journal of pharmaceutical care - 2017 - دوره : 5 - شماره : 1 - صفحه:29 -36
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چکیده
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With the emergence of various developments in determining pathophysiology behind diseases, emergence of resistance against diseases and the need to design an effective treatment against most common infectious and non-infectious diseases, the need of developing more effective drug comes under the limelight. at present, more studies are being carried out on the utilization of monoclonal antibodies as successful therapeutic agents. this include conditions which affect livelihood of people, the most common an widespread diseases, infectious diseases caused by more virulent or drug-resistant microorganisms and viruses and also inherited diseases. current review thus targets cancer, diabetes, autoimmune diseases, hypercholesterolemia, ophthalmology and infectious diseases and briefly discusses the pathophysiology behind the mode of action of the therapeutic agents based on monoclonal antibodies and the benefits and drawbacks of such developed agents. this also focuses on the areas where studies can be carried out to determine effective use of monoclonal antibodies in the future to answer and treat major medical related issues. this review was done using the available literature on monoclonal antibodies and its application through web and pubmed searches. according to our results, monoclonal antibodies plays a major role as clinical and therapeutic agent in curing both communicable and non-communicable diseases.
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کلیدواژه
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monoclonal antibody ,indications ,review
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آدرس
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university of peradeniya, institute of science, sri lanka, university of peradeniya, faculty of medicine, department of microbiology, sri lanka, indian academy degree college-autonomous, department of biotechnology, india
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Authors
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