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endocrine-disrupting chemicals role indrug abuser: a review study
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نویسنده
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wiraagni idha arfianti ,mohd mustafa ali ,rashid rusdi abdul ,mohamad haron didi erwandi bin
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منبع
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international journal of medical toxicology and forensic medicine - 2020 - دوره : 10 - شماره : 4 - صفحه:26324 -26324
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چکیده
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Endocrine-disrupting chemicals (edcs) are exogenous chemicals that influence many aspectsof natural hormone actions. bisphenol is used in the industry, for increasing the thickness anddurability of materials in certain plastics and resins. paraben is used as preservatives in manypharmaceuticals, cosmetics, and some food products. edcs can increase estrogen levelsinside the body, and estrogen itself can increase the monoamine effect (dopamine, serotonin),neuronal excitability, neuropeptide transmitter mechanism, and drug metabolism. in drugabusers, this effect can develop greater craving behavior, addiction, and relapse.
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کلیدواژه
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edcs ,bisphenol ,paraben
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آدرس
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university of malaya, faculty of medicine, department of pathology, department of forensic medicine and medicolegal, iran, university of malaya, shimadzu‐um center for xenobiotics studies (sucxes), faculty of medicine, iran, university of malaya, faculty of medicine, department of psychological medicine, iran, university of malaya, shimadzu‐um center for xenobiotics studies (sucxes), faculty of medicine, iran
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Authors
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