Evaluation of the Status of Immunity to HBV Infection in a Group of Basic Medical Science Students in Tabriz

Background and aims: hepatitis b is a viral infection that attacks the liver and can causeboth acute and chronic disease. thus, the present study focused on antibody titer amonghbv-vaccinated medical students in order to evaluate the efficacy of hepatitis b vaccine andthe associated factors.materials and methods: in this cross-sectional study, 184 medical students were enrolled.blood samples were taken from the participants in order to detection of antibody againsthepatitis bsag by elisa. data analysis was done by chi-square and fisher’s exact tests.results: according to the obtained results, 1.1% of the students had a negative titer, whileanother 53.8 % were in the borderline situation; whereas 45.1% produced a positive titer.furthermore, the results revealed that there was no statistically significant difference betweenhepatitis b antibody titer values and variables such as gender (p<0/05).conclusion: by considering the fact that medical students are at greater risk of hbvinfection, it is necessary to schedule the determination of serum anti-hbs titer to improve theimmunization programs and to decrease the risk of infection before internship program. revaccination(booster shot) is also necessary for people with low titers anti- hbs or lossantibody and controls their antibody titers, and also in who are considered as high-risk groupin the society.