A Novel Genetic classification of SARS coronavirus-2 following whole nucleic acid and protein alignment of the isolated viruses

Background and aims: the end of 2019 has marked the year, which the human populationencountered a novel virus; sars-cov-2 that causes a disease namely covid-19. here wefocused on the genome and protein mutations and subsequently suggested a newclassification of the sars-cov-2.materials and methods: our study showed that some extra positions in the virus genomeplay a key role in the sars-cov-2 classification. based on the analysis of the whole genomesequences of 93 viruses.results: mutations were classified into nine divisions including ia-1, ia-2, ia-3, ib, ii, l1,l2, l3 and s. totally, 279 mutations were found in the sars-cov-2 genomes. 24 mutationslead to the amino acid frame shifting, of which 15 mutations lead to positive frame shifting inamino acids sequences.conclusion: sequence alignment of these positions with that of ancestors showed no changesuggesting that they might have occurred in the sars-cov-2 genomes to adapt itself tohumans.