Paraneoplastic neurologic syndromes

Paraneoplastic neurologic syndromes (pns) are manifestations of cancers located outside the central nervous system. they appears before the diagnosis of cancer in most of the patients. frequency among all cancer patients is 0.01%. they show close association with some kinds of cancer. these disorders occure due to stimulation of immune response by some proteins which are formed by a tumor, against both tumor and the nervous system. for diagnosis, cancer associated with paraneoplastic syndrome should be detected and antibody should be demonstrated. neurologists should be aware of these syndromes so that appropriate diagnostic and treatment options can be applied sooner. because the tumor examination and treatment plan should be made following the diagnosis.