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heart rate variability and cocaine: a systematic review of human studies
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نویسنده
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koenig julian ,menke barbara ,hillecke thomas k. ,thayer julian f. ,jarczok marc n.
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منبع
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archives of neuroscience - 2015 - دوره : 2 - شماره : 1 - صفحه:1 -8
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چکیده
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Cocaine affects the autonomic nervous system (ans). cardiovascular effects of cocaine have been extensively studied by measures of mean heart rate (hr) or blood pressure (bp). the present systematic review aims to summarize the current evidence on the effects of cocaine on heart rate variability (hrv) in human subjects. a systematic search of electronic databases (pubmed, psyndex and embase) based on the “preferred reporting items for systematic reviews and meta-analyses (prisma)” statement was employed. studies were screened for eligibility based on pre-specified inclusion criteria. the search revealed a total of 48 papers after removing duplicates. eleven studies fitting the inclusion criteria were included in the systematic review. evidence on the effects of cocaine on hrv is rare. existing studies either address the impact of acute cocaine administration in adults or the effect of prenatal cocaine exposure on infants in various age groups. however, hrv is a promising index to study ans function within this particular field of research. several suggestions for future research are provided.
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کلیدواژه
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heart rate variability ,cocaine ,humans
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آدرس
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ohio state university, department of psychology, usa, srh university of applied sciences, school of therapeutic sciences, germany, srh university of applied sciences, school of therapeutic sciences, germany, ohio state university, department of psychology, usa, heidelberg university, mannheim institute of public health, social and preventive medicine, germany
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Authors
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