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   Single Nucleotide Polymorphism Analysis of the Bone Morphogenetic Protein Receptor Ib and Growth and Differentiation Factor 9 Genes in Rayini Goats (Capra Hircus)  
نویسنده Mehdizadeh Gazooei Y. ,Niazi A. ,Zamiri M. J.
منبع Journal Of Livestock Science And Technologies - 2013 - دوره : 1 - شماره : 2 - صفحه:45 -50
چکیده    The fecb, a mutation in the bone morphogenetic protein receptor ib (bmpr-ib) gene, which increases the fecundity of booroola merino sheep, and fecg^h, a mutation in the growth and differentiation factor 9 (gdf9), which affects the fecundity of cambridge and belclare sheep in a dose sensitive manner, were analyzed as candidate genes associated with the prolificacy in rayini goats. these polymorphisms were analyzed by pcr-rflp method in 110 individuals randomly se-lected out from a flock of rayini goats with a mean litter size of 1.29. these mutations were not de-tected in this flock. all individuals were wild type homozygous for fecbandfecg^h. these results suggested that fecundity of this breed is not linked to the same loci in bmpr-ib or gdf9 as in some sheep breeds, and other polymorphism(s) may be involved in rayini goat prolificacy. therefore, searching for other polymorphisms in these genes or any polymorphisms in known fecundity genes is suggested to develop marker assistance selection techniques and to study the genetic mechanism of prolificacy in goat.
کلیدواژه Fecundity Gene ,Polymorphism ,Rayini Goat
آدرس Shiraz University, College Of Agriculture, Department Of Animal Science, ایران, Shiraz University, College Of Agriculture, Institute Of Biotechnology, ایران, Shiraz University, College Of Agriculture, Department Of Animal Science, ایران

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