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   investigating the frequency of coagulation abnormality in hospitalized children with covid19: a cross-sectional study  
   
نویسنده karimi rouzbahani arian ,tahmasebi ghorabi samaneh ,mohammadian maryam ,mohammad zadeh maliheh ,goudarzi zahra ,mallahi mahmood ,molavi mohammad ali
منبع journal of pediatric perspectives - 2024 - دوره : 12 - شماره : 4 - صفحه:18700 -18711
چکیده    Background: based on the findings of previous studies, patients with severe covid-19 have a much greater occurrence of coagulation abnormalities. additionally, individuals who get this novel virus are susceptible to developing disseminated intravascular coagulation. the present study aimed to investigate the frequency of coagulation disorders in children with covid-19 who were hospitalized in bandar abbas children’s hospital during 2020-2021.methods: this study was done retrospectively. the medical records of all children were checked with a definite diagnosis of covid-19, based on positive pcr results. age, gender and comorbidity status were obtained from the medical records of the patients. in addition, white blood cell count, blood platelet count, hemoglobin concentration, crp, pt, ptt, inr, d-dimer and fibrinogen were checked. data was analyzed using spss 22 software with a significance threshold of 0.05.results: in this study 20.63% had coagulation abnormalities. the groups with and without coagulation disease exhibited a significant difference in the proportions of neutrophils and lymphocytes. specifically, the coagulation disorder group had elevated levels of neutrophils and reduced levels of lymphocytes (p= 0.043, p= 0.041, respectively). the average d-dimer level and age in the group with coagulation disorder was significantly greater than those in the group without coagulation problem (p= 0.000, p=0.045).conclusion: according to the findings of this research, 20.63% of children who were definitively diagnosed with covid-19 had coagulation abnormalities. only the alterations in d-dimer, lymphocyte, and neutrophil levels were shown to be substantially associated with coagulation disorders in this investigation. specifically, in the group with coagulation disorders, there was an elevation in neutrophil count and a decrease in lymphocyte count.
کلیدواژه covid-19 ,coagulation disorder ,children ,d-dimer
آدرس lorestan university of medical sciences, student research committee, usern officestudent research committee, iran, ilam university of medical sciences, iran, hormozgan university of medical sciences, clinical research development center of children hospital, department of pediatric, iran, hormozgan university of medical sciences, school of medicine, department of pediatrics, iran, tehran university of medical sciences, school of nursing and midwifery, iran, lorestan university of medical sciences, student research committee, iran, pediatric hospital, department of pediatric oncology, iran
پست الکترونیکی shayanmolavi@yahoo.com
 
     
   
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