importance of il-1β in sars-cov-2 infection

Severe acute respiratory syndrome coronavirus 2 (sars-cov-2) provokes the host immune responses and induces severe respiratory syndrome by overreaction of immune cells. il-1β is a pro-inflammatory cytokine highly associated with the related inflammation and cytokine storm, and several il-1β antagonists are being used to treat cytokine release syndrome (crs). accordingly, some studies and clinical trials are investigating the effects of il-1β antagonists for controlling coronavirus disease 2019 (covid-19) associated crs. here, we will review any interaction and association between il-1β and sars-cov-2 infection.