the relationship between bone mineral density and serum vitamin d levels in cystic fibrosis children

Background: cystic fibrosis is a multisystemic disorder. it is the most common autosomal recessive disorder in whites that causes complications such as changes in bone density. therefore, evaluating bone densitometry and serum levels of vitamin d in children with cystic fibrosis is the aim of our study. methods: this study was performed on 54 children with cystic fibrosis. after recording demographic information, bone densitometry and serum levels of vitamin d were recorded. chi-square and pearson correlation tests were used to compare data. results: based on our study 53.7% of patients with cf had vitamin d less than 20 nmol / l. it was also found that based on lumbar bmd, 20.3% had a bmd less than 2.5 - based on femoral bmd, 18.5% had a bmd less than -2.5. and our results demonstrated that there is no relation between bmd with vitamin d, calcium and phosphorus but it is significantly correlated with age, height, weight, and bmi. conclusion: decreased bmd is high in patients with cf; on the other hand there is a deficiency of vitamin d in more than 50% of these patients to whom vitamin d supplements should be prescribed along with the standard treatments. further studies are also required to investigate the effect of other factors on bmd.