evaluation of the ventricular function based on echocardiographic findings in asthmatic children

Background: objective: asthma is a chronic inflammatory disease leading to hypertrophy and dilatation of the right ventricle. this study aims to evaluate and compare left and right ventricular systolic and diastolic functions of the heart based on echocardiographic criteria in children with moderate to severe asthma and non-asthmatic children referred to hazrat rasouland firoozabadi hospitals of tehran in 2019. methods: in this case-control study, 50 patients with a definite diagnosis of moderate to severe asthma (case group) and 50 healthy individuals (control group) were studied and compared in terms of clinical and echocardiographic measures. blood pressure, heart rate, body height and weight of all children were recorded. the patients who were >6 years underwent pulmonary function tests using spirometry. conventional and tdi echocardiography was performed by a single experienced pediatric cardiologist on the two groups blindly and echocardiographic data was collected. results: the results showed that the left ventricular stroke volume was significantly lower in patients with asthma. also, in the right ventricular sv, significantly lower values were found in the group of patients under study than healthy individuals (p=0.01). the e/a ratio in both groups was higher than one; the mean and standard deviations were not significantly different between the case (1.72±0.26) and the control group (1.92±0.32). conclusion: the results of this study showed that asthma can affect ventricular contraction in children. contrary to the previous studies and despite the observation of cardiac systolic dysfunction in patients with asthma, diastolic dysfunction in these patients was not observed even by tissue doppler echocardiography.