Guillain-Barre Syndrome following Cushing's Syndrome in a Pregnant Woman: A Case Report

Guillain-barre syndrome is a neurological disorder that begins with weakness of the limbs and can cause respiratory and cardiac involvement. the subject of this report is a 30-year-old woman who was diagnosed with cushing’s syndrome following recurrent bone fractures and receiving treatment for the cushing’s syndrome. the patient was referred to a hospital during pregnancy because of generalized pain and weakness in the extremities. abdominal ultrasound showed a mass in the left adrenal gland and so surgery was performed to remove the mass. however, the patient's symptoms did not improve after surgery. the patient was asked to consult a neurologist who made a diagnosis of guillain-barre syndrome after cerebrospinal fluid was examined. patient was discharged with personal consent. four months later, the baby was born with a normal apgar score, and the general condition of mother and child were evaluated as good. this case demonstrates a rare coincidence of cushing's disease and guillain-barre syndrome. due to the increase in corticosteroids due to cushing's syndrome, it is expected that symptoms of guillain-barre syndrome would not occur. this case could indicate that there are several mechanisms for development of guillain-barre syndrome and that animal models can be helpful in this context.