Clinical Findings of Infants Born to an HIV-Positive Mother: A Hospital Based Case-Control Study in Tehran, Iran

Background there are contradictory results regarding association between maternal hiv infection and neonatal adverse outcomes. therefore, in this study the neonates born from hiv-positive mothers compared with hiv-negative mothers were assessed in tehran, iran. materials and methods this retrospective case-control study was conducted on 50 infants born to an hiv-positive mother compared with 53 infants born to an hiv-negative mother as control group, during 8 years of a period from 2006-2015, admitted in valiasr hospital of tehran. data were gathered from medical records of patients. results all children (n=53, 100%) in the case group were born through cesarean section; while 20.75% of the control group children were born by natural delivery (p=0.001). there was statistically significant difference between neonates born from hiv-positive mothers compared to hiv-negative mothers with respect to delivery method and gender (p<0.05). the mean weights (gr) were higher in the controls than the cases (3052.830±380.71 vs. 2731.80±575.90) (p=0.001). also, a significantly increased hemoglobin was observed in the controls (15.87±1.97 g/dl) compared to the cases (13.42±1.69 g/dl) (p=0.001). liver functions test (lfts) was significantly higher in case groups (p=0.005). conclusion based on the results, the mean weight and hemoglobin were lower in infants born from hiv-positive women compared with hiv-negative women. also, lft disorder was higher in infants born from hiv-positive women compared with hiv-negative women.