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   Genital Involvement in Pre-Pubertal Pediatric Population: a Rare Aspect of Crohn’s Disease  
   
نویسنده warsi qurratul ann ,kunduru meghana ,karjoo manoochehr ,beg mirza
منبع journal of pediatric perspectives - 2016 - دوره : 4 - شماره : 9 - صفحه:3399 -3404
چکیده    Crohn’s disease is an inflammatory bowel disease (ibd), characterized by chronic intestinal inflammation that causes the loss of immune tolerance leading to bizarre inflammatory signals and disruption of mucosal barriers. environmental triggers and interaction of genetic determinants also play an indispensible role. in this case report, we present a pre-pubertal girl with intermittent and refractory genital swelling. we emphasize that crohn’s disease must be considered in the differential diagnosis of recurrent, non-tender, erythematous and edematous lesions of the genital area. we conclude with future directions for diagnosing and managing vulvar crohn’s disease in pediatric population.
کلیدواژه Crohn’s disease (CD) ,Inflammatory Bowel Disease (IBD) ,Infliximab ,Tumor necrosis factor alpha (TNF-α) ,Vulvar swelling
آدرس university of california and san francisco, department of epidemiology and biostatistics, USA, state university of new york medical university, USA, suny upstate medical university, division of pediatric gastroenterology, hepatology, and nutrition, USA, suny upstate medical university, division of pediatric gastroenterology, hepatology, and nutrition, USA
 
     
   
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