IL-1β Genetic Polimorphism in Menopause Women as Periodontal Disease Risk Factor

Periodontal disease is a disease with multifactorial etiology that can occur in postmenopausal women. objective: this research aims to know the description of the genetic polymorphism of il-1β in postmenopausal women in indonesia as a risk factor for periodontal disease. methods: this study is a descriptive study on 55 biological stored amples. sample’s extracted dna was analysed for polymorphisms il-1β+3954 using pcr-rflp method with taqα1 restriction enzyme digests then the result was electroforized. research results were analyzed using chi square test. results: the genotype cc frequency was 85.7%, ct 14.3%, and tt was absent in normal people. cc 86.5%, ct 8.3%, and tt did not exist in people who have periodontal disease. conclusion: genetic polymorphisms il-1β in indonesia’s postmenopausal women is not a risk factor for periodontal disease