efficacy of indigenous bacteria with quorum quencher properties on biochemical factors of common carp (cyprinus carpio)

In this study, efficacy of two main probiotics (citrobacter freundii and bacillus foraminis) with indigenous quorum quenching (qq) isolated from the intestine of cyprinus carpio was studied on haemato-innate immune responses, antioxidant capacity and disease resistance of this fish species. juveniles of c. carpio (n=450, weighing 50±10 g) were randomly divided into 6 equal groups (with 3 replications) and were fed on diets containing 1×109 cfu g-1 of c. freundii (qq1, g1), b. foraminis (qq2,r g2), l. plantarum (without characteristics qq, wqq, g3), qq1 + qq2 (g4), qq1 + qq2+wqq (combine, g5), and a control diet (without probiotic) for 60 continuous days. our results showed, alkaline phosphatase (alp) levels increased in qq2 at 30 days but it declined later, while ast and alt activities varied among treatments. serum triglycerides, total protein, albumin, glucose  and urea were significantly different in the probiotic treatments compared control group (p<0.05). overall, indigenous probiotics improved various health parameters and reduced side effects in treated fish.