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vitamin d status in osteoporotic and diabetic patients and athletic healthy individuals from northern greece
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نویسنده
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anetakis constantine ,mitka stella ,chatzidimitriou maria ,anagnostopoulos konstantinos ,eleftheriou phaedra ,lialiaris theodoros
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منبع
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reports of biochemistry and molecular biology - 2023 - دوره : 11 - شماره : 4 - صفحه:565 -576
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چکیده
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Background: vitamin d deficiency is recognised as a pandemic in the developed world. however, the importance of prudent sun exposure tends to be overlooked, which is responsible for this pandemic.methods: we investigated the vitamin d status in 326 adults, 165 females and 161 males: 99 osteoporosis patients, 53 type 1 diabetes patients, 51 type 2 diabetes patients, and 123 athletic healthy individuals, from northern greece, through the measurement of total calcidiol in winter and summer by immunoenzymatic assay.results: in the whole sample 23.31% had severe deficiency, 13.50% mild deficiency, 17.48% insufficiency, and 45.71% adequacy at the end of winter. mean concentrations differed significantly (p <0.001) between males and females. the prevalence of deficiency in the young was significantly lower than in the middle-aged (p = 0.004) and in the elderly (p <0.001), while it was significantly lower (p = 0.014) in the middle-aged than in the elderly. the best vitamin d status was found in the athletic healthy individuals, followed by the type 1 and type 2 diabetic patients, while osteoporotic patients had the poorest status. the difference in mean concentrations between winter and summer was significant (p <0.001).conclusions: vitamin d status deteriorated with increasing age and it was better in males than in females. our findings suggest that outdoor physical activity in a mediterranean country can cover the vitamin d needs of the young and the middle-aged, but not of the elderly, without the need for dietary supplements.
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کلیدواژه
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total calcidiol ,osteoporosis ,type 1 diabetes ,type 2 diabetes ,vitamin d status.
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آدرس
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international hellenic university, alexandrian campus, faculty of biomedical sciences, school of health sciences, laboratory of clinical chemistry, greece, international hellenic university, alexandrian campus, faculty of biomedical sciences, school of health sciences, laboratory of clinical chemistry, greece, international hellenic university, alexandrian campus, faculty of biomedical sciences, school of health sciences, laboratory of clinical chemistry, greece. bioanalysis diagnostic laboratory, greece, democritus university of thrace, faculty of medicine, school of health sciences, greece, international hellenic university, alexandrian campus, faculty of biomedical sciences, school of health sciences, laboratory of clinical chemistry, greece, democritus university of thrace, faculty of medicine, school of health sciences, greece
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Authors
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