Niyangala (Gloriosa Superba) Poisoning Complicated with SIADH

Background: niyangala poisoning used to be a common method of deliberate self-harm among people living in rural areas of srilanka. it is a plant that grows in the wild and has no usage. all parts of this plant are poisonous.the toxic ingredient in niyangala iscolchicine. even though colchicine poisoning is uncommon, it can lead to life threatening complications and be considered atoxicological emergency. it can cause severe gastroenteritis, abdominal pain, hypotension, electrolyte imbalance in the initial phase,as well as granulocytopenia, thrombocytopenia, clotting defects, hepatic insufficiency and renal failure after the first 24 hours.case presentation: a 62-year-old male presented to our medical unit with several episodes of severe watery diarrhea 6 hours after theingestion of 3 tubers of niyangala. he also had epigastric pain, nausea and vomiting. he had eaten niyangala after consuming alcoholand claimed it was after a dispute with his wife. on admission, the patient was in pain with some dehydration but he was afebrile.discussion: siadh consists of hyponatremia, inappropriately elevated urine osmolality (>100 mosm/kg), and decreased serumosmolality in a euvolaemic patient. siadh should be diagnosed when these findings occur in the setting of otherwise normal cardiac,renal, adrenal, hepatic, and thyroid function; in the absence of diuretic therapy; and in the absence of other factors known to stimulateadh secretion, such as hypotension, severe pain, nausea, and stress.conclusion: siadh is a well-recognized complication of colchicine poisoning. we report for the first time siadh after the ingestionof tubers of gloriosa superba. hyponatremia in a patient after poisoning with gloriosa superba is usually attributed to severe diarrheawhich is a common and dominant clinical feature often managed with fluid replacement.