Effects of Diesel Combustion Nanoparticles on Oxidative Stress Markers among the Exposures

Background: although studies are available on lipid peroxidation products and the antioxidant status in experimental animals, a detailed report on human exposed to diesel combustion nanoparticles is meagre. we aimed to study the variation in oxidative stress markers among exposures.method: a cross-sectional study during the period between 2015-2017 was conducted among 500 male garage workers of age group 25-40 years with history of exposure for 6-8 hrs a day without using any protective aids during work, for 6-12 years and 300 controls, who live in hilly areas where they were sparsely exposed. serum oxidative stress markers were estimated and compared.results: a significant variation was observed among the oxidative stress markers in exposures with surge in melanaldehyde (mda) and reduction in superoxide dismutase (sod) and catalase (cat).conclusion: unprotected exposure to diesel combustion products induces oxidative stress which can alter recordable change among the markers. oxidative stress, being the route cause for cell.