association of troponin-i level on admission with 6-month clinical consequences in acute coronary syndrome patients: a preventive approach in patient care

Background: cardiovascular diseases are the leading cause of mortality worldwide. therefore, it is important to predict the future consequences of the disease in patients who have recovered.objectives: we sought to determine the relationship between troponin-i level and 6-month clinical consequences (i.e., re-infarction, death, re-angiography and coronary artery bypass grafting) in patients with acute coronary syndrome (acs).methods: this prospective cross-sectional study was performed among 60 patients with acs admitted to ayatollah mousavi hospital in zanjan, iran. the participants were chosen using the convenience sampling method. troponin-i level in these patients was initially evaluated. afterwards, they were followed up for six months in terms of clinical consequences. a checklist was prepared to collect the required data. the receiver operating characteristic (roc) analysis was conducted to determine the predictive power of high-sensitivity troponin i for the mentioned consequences. iodine index was calculated to determine the cutoff point for this enzyme in order to predict the consequences.results: in general, 66.2% of the participants were male and the mean age was 60.46 ± 12.78 years. we found that 21.2% of the participants experienced one of the four clinical consequences in the follow-up period of 6 months. the sub-curved surface was calculated to be 0.705 for the prediction of consequences. the cutoff point for the prediction of consequences was 32.5; the negative predictive value for the cutoff point was 32.5, which was equal to 89.8%.conclusion: troponin-i has an acceptable predictive power to identify 6-month consequences of acs. moreover, considering the negative predictive value of troponin-i, it is recommended to use this biomarker in patients with acs. in addition, healthcare providers should pay more attention to the follow-up of patients after discharge and design preventive programs.