evaluation of the diurnal intraocular pressure fluctuations and blood pressure under dehydration due to fasting

Introduction: this study aimed to investigate the diurnal intraocular pressure fluctuations under dehydration conditions and the relationship between the intraocular pressure fluctuations and blood pressure. methods: the intraocular pressures (iop), body weights, as well as systolic and diastolic blood pressures (sbp, dbp) of 36 fasting healthy volunteers were recorded at 8:00 a.m. and 5:00 p.m. in the ramadan of 2014 and two weeks after it. the data were analyzed using paired student’s t-test and pearson correlation analysis. results: as the results demonstrated, the mean diurnal iop differences of iop, sbp, dbp, and weight were 2.67±1.33 mmhg, 9.44±8.02 mmhg, 3.33±5.94 mmhg, and 0.90±0.46 kg during the fasting period, respectively. in addition, the mean diurnal iop differences of iop, sbp, dbp, and weight were - 0.33±1.4 mmhg (p=0.001), 0.55±7.25mmhg (p=0.003), -3.33±5.94 mmhg (p=0.001), and 0.12±0.45 kg (p=0.001) during the control period, respectively. there was a moderate correlation between the diurnal iop and sbp differences (r=0.517, p=0.028). conclusion: based on the findings of the current study, the total fluid volume might have a more dominant effect on iop peaks than the sympathetic system activity. furthermore, the sbp was found to correlate with the iop.